Research

Carbohydrate Synthesis:

The main focus of our research is the development of new methods for transition metal-catalyzed stereoselective glycosylation reactions. Additionally, we are dedicated to exploring novel strategies for site-specific modifications of free protected saccharides. 

Through these research efforts, we hope to advance the field of glycochemistry and provide valuable insights and tools for the synthesis and modification of complex carbohydrates, which can have important implications in drug development and other areas of chemical biology.

  • 开发过渡金属催化立体选择性糖苷化的新方法

  • 发展无保护糖类精准定点修饰的新策略

Peptide and Protein Modification:

Our aim is to create innovative approaches and  strategies for introducing specific functional groups or modifications into peptide and protein structures with high efficiency and precision.

By advancing the field of peptide and protein chemical modification, we aim to facilitate research in areas such as drug development, targeted drug delivery, and the study of protein function and interactions. The development of new methods and strategies in this area has the potential to significantly impact various fields of life sciences and medicine.

  • 开发多肽与蛋白质化学修饰的新方法与新策略

Glycopeptide and Glyprotein Synthesis:

In our research, we are actively focused on developing new methods and strategies for the large-scale preparation of homogeneous glycopeptides and glycoproteins. Glycopeptides and glycoproteins are complex molecules with important biological functions, and they hold great potential for applications in various fields, including biology, medicine, and vaccine development. 

  • 开发规模化制备均质糖肽和糖蛋白的新方法和新策略

Glycobiology and Chembiology:

In our Chemical Biology research, we will focus on investigating the interactions and functions of saccharides, polypeptides and proteins, glycoconjugates, and other related molecules. Our main goal is to gain a deeper understanding of the biological processes involving carbohydrates and their conjugates, and to explore their potential as therapeutic agents.

  • 开展糖类、蛋白质、糖缀合物等生物大分子的化学生物学研究,致力于创制具有重要社会和经济价值的变革性糖类药物